Investigator(s)
| WHO Technical Officer |
Ela Singh Rathaur WHO Nepal Ela Singh Rathaur 
|
| Principal Investigator |
Nira Joshi Research Director, New Era Nira Joshi
|
| Co-Investigator(s) |
Rahul Pradhan National Professional Officer, Immunization Cluster Lead, WHO-IPD, Nepal Rahul Pradhan
|
| Co-Investigator(s) |
Pawan Upadhyaya New Vaccines and Immunization Program Support Officer, WHO-IPD, Nepal Pawan Upadhyaya
|
| Co-Investigator(s) |
Raj Kumar Sangroula Research Officer Raj Kumar Sangroula
|
Title(s) and abstract
| Scientific title | Post Campaign Coverage Survey (PCCS) of MeaslesRubella (MR) Vaccination Campaign 2024 in Nepal |
| Public title | Post Campaign Coverage Survey (PCCS) of MeaslesRubella (MR) Vaccination Campaign 2024 in Nepal |
| Background | A nationwide measles-rubella (MR) vaccination campaign was conducted by the Ministry of Health and Population with operational costs and vaccine support from Gavi, the Vaccine Alliance, from 25 February 2024 to 20 March 2024 in a modular approach. The first approach consisted of a nationwide non-selective campaign targeting all children aged 9 months to under 5 years and second approach included additional 5 years to under 15 years in 24 high-risk districts irrespective of their measles/measles-rubella vaccination history. The MR campaign also integrated catch-up vaccination with Pentavalent vaccine (DPT-HepB-HiB), Pneumococcal Conjugate Vaccine (PCV) and Inactivated Polio Vaccine (IPV) for children who have missed routine immunization doses, to provide one or more missed doses. Given the context, with the objective of evaluating national and modular MR vaccination campaign coverage, a post campaign coverage survey (PCCS) is designed based on the latest guideline of WHO on immunization coverage estimation survey. |
| Objectives | Primary Objectives • Estimate the proportion of children aged 9 months to under 5 years at the time of vaccination campaign in all districts who were vaccinated with measles rubella vaccine in the nation-wide campaign conducted during February-March 2024 (Coverage of module 1). • Estimate the proportion of children aged 5 years to under 15 years in the 24 high risk districts at the time of campaign who were vaccinated with measles-rubella vaccine in the nation-wide vaccination campaign conducted during February-March 2024 (Coverage of Module 2). |
| Study Methods | This survey is a cross-sectional, population-based, nationally representative study using a two-stage cluster sampling design, in line with WHO guidelines for immunization coverage estimation. It targets children aged 9 to 59 months in 75 districts and children aged 5 to under 15 years in 24 high-risk districts as part of the 2024 MR (Measles-Rubella) campaign. A total of 262 clusters will be selected using Probability Proportional to Size (PPS) sampling, with 131 clusters drawn from each of two strata (51 districts and 24 high-risk districts). In the first stage, clusters will be selected from the census-2021 enumeration area, with larger clusters divided into segments. Twenty-two households per cluster will be chosen using systematic random sampling, and a Kish grid will be used to select one eligible child per household. The child's mother or caretaker will be the primary respondent for the survey. |
| Expected outcomes and use of results | This survey will estimate national coverage among children aged 9 months to under 5 years and evaluate coverage among the 5 to under 15 years age group in 24 high-risk districts. Additionally, it will provide detailed coverage estimates in two strata: the first covering children aged 9 months to under 5 years and the second including both 9 months to under 5 years and 5 to under 15 years in the high-risk districts. The data generated through this study will seek to address knowledge gaps in the existent body of evidence, examine what works and what is missing, document best practices and opportunities for conducting campaigns related to immunization. |
| Keywords | measles-rubella (MR), Vaccinaiton, campaign, Postcampaign coverage survey, catch up |
Research Details
| Student research | No |
| Start Date | 19-Sep-2024 |
| End Date | 18-Feb-2025 |
| Key Implementing Institution | NewERA |
| Multi-country research | No |
| Nationwide research | Yes |
| Research Domain(s) | Maternal, Reproductive and Child Health |
| Research field(s) | Immunization/Vaccine Preventable Disease |
| Involves human subjects | No |
| Data Collection | Primary data |
| Proposal reviewed by other Committee | Under Review |