Investigator(s)
| WHO Technical Officer |
Mona NA Lacoul WHO Mona NA Lacoul 
|
| Principal Investigator |
Samir Mani Dixit Founder Director of Research-Public Health Center for Molecular Dynamics Nepal (CMDN) Samir Mani Dixit
|
| Co-Investigator(s) |
Kavya Sharma Project Manager IQVIA Consulting & Information Services India Pvt. Ltd. Kavya Sharma
|
| Co-Investigator(s) |
Lakshya Sharma IT Officer IQVIA Consulting & Information Services India Pvt. Ltd. Lakshya Sharma
|
Title(s) and abstract
| Scientific title | Post campaign coverage survey for Typhoid Conjugate Vaccination Campaign-2022 in Nepal |
| Public title | Post campaign coverage survey for Typhoid Conjugate Vaccination Campaign-2022 in Nepal |
| Background | The National Immunization Program (NIP) in Nepal is a priority initiative of the government, which began in 1979 and expanded nationwide by 1988. The program currently includes 13 antigens, with the recent addition of the Typhoid Conjugate Vaccine (TCV) to the routine immunization schedule. Nepal, being a highly burdened country for typhoid, introduced the typhoid vaccine in May 2022 after recommendations from advisory committees. Before its introduction, a catch-up vaccination campaign was conducted from April to May 2022, targeting children aged 15 months to 14 years. The campaign achieved 95% national coverage, although there was a gap in the youngest age group. The campaign also included activities to strengthen routine immunization and link it with the catch-up campaign. Nepal is the fourth country to introduce Typhoid vaccines in the routine program with support from GAVI. A post-campaign coverage survey is planned to assess program performance and may include additional components such as evaluating the linkage mechanism between routine immunization and supplementary immunization activities. |
| Objectives | General Objective: • To estimate the proportion of children aged 15 months to 14 years at the time of the campaign (national and provincial) who were vaccinated against typhoid during the national catch-up campaign conducted during April/May 2022 • To estimate the proportion of children aged 12-23 and 24-35 months at the time of the survey (national and provincial) who have received vaccination for each of the vaccines recommended in the national immunization schedule for Nepal (except TCV through RI). Specific Objectives: • To assess awareness of the national typhoid vaccination campaign among the mothers/caretakers of the eligible children. • To assess behavioral and social drivers (BeSD) for vaccination and their relation with non-participation in national typhoid vaccination campaign among the mothers/caretakers of eligible children who did not receive the vaccines in the campaigns. • To assess the proportion of 15-35 months children who received zero dose or one dose of measles rubella vaccine in routine were identified during the national catch-up campaign conducted during April/May 2022 (among campaign card holders) |
| Study Methods | This is a cross-sectional study which will be carried out nationwide including seven provinces where household visits will be done. Mothers/caretakers of eligible children will be respondents of the survey. A two stage probability proportional to size sampling method will be used to select clusters and household in each province. Data will be collected by a standard questionnaire which has been developed based on the previous round of MR survey and the tool will be pretested. Data will be collected in electronic version-CAPI with GPS coordinates and for this tablets will be utilized. The CAPI collected data will be synchronized with central server in Kathmandu. For data analysis, preliminary analyses will be performed using SPSS/R program. Exploratory data analysis encompassing graphical plot/s and numerical test/s will be carried out. Data will be analyzed by conducting descriptive statistics and bivariate analysis for calculating the coverage and other relevant indicators. |
| Expected outcomes and use of results | The study will determine the proportion of children reached in the TCV campaign with estimating the TCV coverage among < 5 years’ children and 5-15 years children. Also the national and provincial coverage. Moreover, the Routine immunization coverage for two age cohorts will also be determined. The study will further outline the factors related to vaccination and with immunization coverage. |
| Keywords | Population based survey, Post campaign coverage survey |
Research Details
| Student research | No |
| Start Date | 08-May-2023 |
| End Date | 31-Oct-2023 |
| Key Implementing Institution | Center for Molecular Dyanmics |
| Multi-country research | Yes |
| Bhutan | |
| Nationwide research | Yes |
| Research Domain(s) | Health Systems Research |
| Research field(s) | Child Health |
| Involves human subjects | Yes |
| Population-Based Survey | |
| Data Collection | Primary data |
| Proposal reviewed by other Committee | Under Review |